Guides by Lonely Planet
Santiago travel | Panama - Lonely Planet
Explore Santiago holidays and discover the best time and places to visit. | Halfway between Panama City and the Costa Rican border and just north of the Península de Azuero, Santiago is a bustling hub of rural commercial activity. There's no real reason to stop here, though it’s a good place to break up a long drive and recharge for the night.Most of Santiago's commerce and services, including stores, banks, gas stations, restaurants and hotels, are along the Interamericana and Av Central, which runs to the west from the highway.